The mature segment forms active ligand dimers through a disulfide-rich core composed of a characteristic "cysteine knot"
It is a major synaptic scaffolding protein that contains three PDZ domains
high-affinity receptor subunit (alpha chain) prior to binding to gp130
making it a significant interest as a potential therapeutic target
initiating downstream signaling pathways that lead to T cell proliferation
LONP1 Rabbit Polyclonal Antibody Secondary Antibody The mature segment forms activeProduct Specification Host Rabbit Antigen LONP1 Synonyms Lon protease homolog, mitochondrial; LONHs; Lon protease like protein (LONP); Mitochondrial ATP dependent protease Lon; Serine protease 15; PRSS15 Immunogen Synthetic Peptide Location Mitochondrion Accession P36776 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK 293, HeLa, SH SY5Y, Jurkat, NIH 3T3, C6 Predicted Reactivity Bv